CharBot: A Simple and Effective Method for Evading DGA Classifiers

Domain generation algorithms (DGAs) are commonly leveraged by malware to create lists of domain names which can be used for command and control (C&C) purposes. Approaches based on machine learning have recently been developed to automatically detect generated domain names in real-time. In this work, we present a novel DGA called CharBot which is capable of producing large numbers of unregistered domain names that are not detected by state-of-the-art classifiers for real-time detection of DGAs, including the recently published methods FANCI (a random forest based on human-engineered features) and LSTM.MI (a deep learning approach). CharBot is very simple, effective and requires no knowledge of the targeted DGA classifiers. We show that retraining the classifiers on CharBot samples is not a viable defense strategy. We believe these findings show that DGA classifiers are inherently vulnerable to adversarial attacks if they rely only on the domain name string to make a decision. Designing a robust DGA classifier may, therefore, necessitate the use of additional information besides the domain name alone. To the best of our knowledge, CharBot is the simplest and most efficient black-box adversarial attack against DGA classifiers proposed to date

CharBot : a simple and effective method for evading DGA classifiers

Domain generation algorithms (DGAs) are commonly leveraged by malware to create lists of domain names, which can be used for command and control (C&C) purposes. Approaches based on machine learning have recently been developed to automatically detect generated domain names in real-time. In this paper, we present a novel DGA called CharBot, which is capable of producing large numbers of unregistered domain names that are not detected by state-of-the-art classifiers for real-time detection of the DGAs, including the recently published methods FANCI (a random forest based on human-engineered features) and LSTM.MI (a deep learning approach). The CharBot is very simple, effective, and requires no knowledge of the targeted DGA classifiers. We show that retraining the classifiers on CharBot samples is not a viable defense strategy. We believe these findings show that DGA classifiers are inherently vulnerable to adversarial attacks if they rely only on the domain name string to make a decision. Designing a robust DGA classifier may, therefore, necessitate the use of additional information besides the domain name alone. To the best of our knowledge, the CharBot is the simplest and most efficient black-box adversarial attack against DGA classifiers proposed to date

Acupuncture for menstruation-related migraine prophylaxis:A multicenter randomized controlled trial

OBJECTIVE: The aim of this study was to evaluate the efficacy of acupuncture, an alternative medicine therapy, as a preventive treatment for menstruation-related migraine (MRM). PATIENTS AND METHODS: This was a prospective, multicenter, double-dummy, participant-blinded, randomized controlled clinical trial conducted in China between 1 April 2013, and 30 April 2014. The participants were enrolled from four study centers and randomized to into either the acupuncture group, which received 24 sessions of acupuncture at traditional acupoints plus placebo, or the medication group, which received sham acupuncture plus naproxen. The primary endpoint was change from the baseline average number of migraine days per perimenstrual period over cycles 1−3. The secondary endpoints included changes from the baseline average number of migraine days outside the perimenstrual period, mean number of migraine hours during and outside the perimenstrual period, mean visual analog scale score during and outside the perimenstrual period, ≥50% migraine responder rate, and the proportion of participants who used acute pain medication over cycles 1−3 and 4−6. RESULTS: A total of 172 women with MRM were enrolled; 170 in the intention-to-treat analyses. Our primary outcome reported a significant between-group difference that favored the acupuncture group (95% CI, 0.17–0.50; P < 0.001), with the average reduction of migraine days per perimenstrual period from the baseline was 0.94 (95% CI, 0.82–1.07) in the acupuncture group and 0.61 (95% CI, 0.50–0.71) in the medication group over cycles 1−3. CONCLUSION: This study showed that compared to medication, acupuncture reduces the number of migraine days experienced by patients with MRM. For patients who received the acupuncture treatment over three cycles, the preventive effect of the therapy was sustained for six cycles. CLINICAL TRIAL REGISTRATION: [https://www.isrctn.com/ISRCTN57133712], identifier [ISRCTN15663606]

2-point statistics covariance with fewer mocks

We present an approach for accurate estimation of the covariance of 2-point correlation functions that requires fewer mocks than the standard mock-based covariance. This can be achieved by dividing a set of mocks into jackknife regions and fitting the correction term first introduced in Mohammad & Percival (2022), such that the mean of the jackknife covariances corresponds to the one from the mocks. This extends the model beyond the shot-noise limited regime, allowing it to be used for denser samples of galaxies. We test the performance of our fitted jackknife approach, both in terms of accuracy and precision, using lognormal mocks with varying densities and approximate EZmocks mimicking the DESI LRG and ELG samples in the redshift range of z = [0.8, 1.2]. We find that the Mohammad-Percival correction produces a bias in the 2-point correlation function covariance matrix that grows with number density and that our fitted jackknife approach does not. We also study the effect of the covariance on the uncertainty of cosmological parameters by performing a full-shape analysis. We find that our fitted jackknife approach based on 25 mocks is able to recover unbiased and as precise cosmological parameters as the ones obtained from a covariance matrix based on 1000 or 1500 mocks, while the Mohammad-Percival correction produces uncertainties that are twice as large. The number of mocks required to obtain an accurate estimation of the covariance for 2-point correlation function is therefore reduced by a factor of 40-60.Comment: 13 pages, 14 figures, submitted to MNRA

PROVABGS: The Probabilistic Stellar Mass Function of the BGS One-Percent Survey

We present the probabilistic stellar mass function (pSMF) of galaxies in the DESI Bright Galaxy Survey (BGS), observed during the One-Percent Survey. The One-Percent Survey was one of DESI's survey validation programs conducted from April to May 2021, before the start of the main survey. It used the same target selection and similar observing strategy as the main survey and successfully observed the spectra and redshifts of 143,017 galaxies in the $r < 19.5$ magnitude-limited BGS Bright sample and 95,499 galaxies in the fainter surface brightness and color selected BGS Faint sample over $z < 0.6$. We derive pSMFs from posteriors of stellar mass, $M_*$, inferred from DESI photometry and spectroscopy using the Hahn et al. (2022a; arXiv:2202.01809) PRObabilistic Value-Added BGS (PROVABGS) Bayesian SED modeling framework. We use a hierarchical population inference framework that statistically and rigorously propagates the $M_*$ uncertainties. Furthermore, we include correction weights that account for the selection effects and incompleteness of the BGS observations. We present the redshift evolution of the pSMF in BGS as well as the pSMFs of star-forming and quiescent galaxies classified using average specific star formation rates from PROVABGS. Overall, the pSMFs show good agreement with previous stellar mass function measurements in the literature. Our pSMFs showcase the potential and statistical power of BGS, which in its main survey will observe >100$\times$ more galaxies. Moreover, we present the statistical framework for subsequent population statistics measurements using BGS, which will characterize the global galaxy population and scaling relations at low redshifts with unprecedented precision.Comment: 25 pages, 12 figures; data used to generate figures is available at https://doi.org/10.5281/zenodo.8018936; submitted to Ap

Validation of semi-analytical, semi-empirical covariance matrices for two-point correlation function for Early DESI data

We present an extended validation of semi-analytical, semi-empirical covariance matrices for the two-point correlation function (2PCF) on simulated catalogs representative of Luminous Red Galaxies (LRG) data collected during the initial two months of operations of the Stage-IV ground-based Dark Energy Spectroscopic Instrument (DESI). We run the pipeline on multiple extended Zel'dovich (EZ) mock galaxy catalogs with the corresponding cuts applied and compare the results with the mock sample covariance to assess the accuracy and its fluctuations. We propose an extension of the previously developed formalism for catalogs processed with standard reconstruction algorithms. We consider methods for comparing covariance matrices in detail, highlighting their interpretation and statistical properties caused by sample variance, in particular, nontrivial expectation values of certain metrics even when the external covariance estimate is perfect. With improved mocks and validation techniques, we confirm a good agreement between our predictions and sample covariance. This allows one to generate covariance matrices for comparable datasets without the need to create numerous mock galaxy catalogs with matching clustering, only requiring 2PCF measurements from the data itself. The code used in this paper is publicly available at https://github.com/oliverphilcox/RascalC.Comment: 19 pages, 1 figure. Code available at https://github.com/oliverphilcox/RascalC, table and figure data available at https://dx.doi.org/10.5281/zenodo.775063

Long-term follow-up observations of extreme coronal line emitting galaxies

We present new spectroscopic and photometric follow-up observations of the known sample of extreme coronal line emitting galaxies (ECLEs) identified in the Sloan Digital Sky Survey (SDSS). With these new data, observations of the ECLE sample now span a period of two decades following their initial SDSS detections. We confirm the nonrecurrence of the iron coronal line signatures in five of the seven objects, further supporting their identification as the transient light echoes of tidal disruption events (TDEs). Photometric observations of these objects in optical bands show little overall evolution. In contrast, mid-infrared (MIR) observations show ongoing long-term declines. The remaining two objects had been classified as active galactic nuclei (AGN) with unusually strong coronal lines rather than being TDE related, given the persistence of the coronal lines in earlier follow-up spectra. We confirm this classification, with our spectra continuing to show the presence of strong, unchanged coronal-line features and AGN-like MIR colours and behaviour. We have constructed spectral templates of both subtypes of ECLE to aid in distinguishing the likely origin of newly discovered ECLEs. We highlight the need for higher cadence, and more rapid, follow-up observations of such objects to better constrain their properties and evolution. We also discuss the relationships between ECLEs, TDEs, and other identified transients having significant MIR variability.Comment: Submitted to MNRAS. 33 pages, 15 figure

The DESI One-Percent Survey: Exploring the Halo Occupation Distribution of Luminous Red Galaxies and Quasi-Stellar Objects with AbacusSummit

We present the first comprehensive Halo Occupation Distribution (HOD) analysis of the DESI One-Percent survey Luminous Red Galaxy (LRG) and Quasi-Stellar Object (QSO) samples. We constrain the HOD of each sample and test possible HOD extensions by fitting the redshift-space galaxy 2-point correlation functions in 0.15 < r < 32 Mpc/h in a set of fiducial redshift bins. We use AbacusSummit cubic boxes at Planck 2018 cosmology as model templates and forward model galaxy clustering with the AbacusHOD package. We achieve good fits with a standard HOD model with velocity bias, and we find no evidence for galaxy assembly bias or satellite profile modulation at the current level of statistical uncertainty. For LRGs in 0.4 < z < 0.6, we infer a satellite fraction of fsat = 11+-1%, a mean halo mass of log10 Mh = 13.40+0.02-0.02, and a linear bias of blin = 1.93+0.06-0.04. For LRGs in 0.6 < z < 0.8, we find fsat = 14+-1%, log10 Mh = 13.24+0.02-0.02, and blin = 2.08+0.03-0.03. For QSOs, we infer fsat = 3+8-2%, log10 Mh = 12.65+0.09-0.04, and blin = 2.63+0.37-0.26 in redshift range 0.8 < z < 2.1. Using these fits, we generate a large suite of high-fidelity galaxy mocks. We also study the redshift-evolution of the DESI LRG sample from z = 0.4 up to z = 1.1, revealing significant and interesting trends in mean halo mass, linear bias, and satellite fraction.Comment: Submitted to MNRAS, comments welcom

mTOR signalling, embryogenesis and the control of lung development

The existence of a nutrient sensitive “autocatakinetic” regulator of embryonic tissue growth has been hypothesised since the early 20th century, beginning with pioneering work on the determinants of foetal size by the Australian physiologist, Thorburn Brailsford-Robertson. We now know that the mammalian target of rapamycin complexes (mTORC1 and 2) perform this essential function in all eukaryotic tissues by balancing nutrient and energy supply during the first stages of embryonic cleavage, the formation of embryonic stem cell layers and niches, the highly specified programmes of tissue growth during organogenesis and, at birth, paving the way for the first few breaths of life. This review provides a synopsis of the role of the mTOR complexes in each of these events, culminating in an analysis of lung branching morphogenesis as a way of demonstrating the central role mTOR in defining organ structural complexity. We conclude that the mTOR complexes satisfy the key requirements of a nutrient sensitive growth controller and can therefore be considered as Brailsford-Robertson's autocatakinetic centre that drives tissue growth programmes during foetal development

Local primordial non-Gaussianity from the large-scale clustering of photometric DESI luminous red galaxies

We use angular clustering of luminous red galaxies from the Dark Energy Spectroscopic Instrument (DESI) imaging surveys to constrain the local primordial non-Gaussianity parameter fNL. Our sample comprises over 12 million targets, covering 14,000 square degrees of the sky, with redshifts in the range 0.2< z < 1.35. We identify Galactic extinction, survey depth, and astronomical seeing as the primary sources of systematic error, and employ linear regression and artificial neural networks to alleviate non-cosmological excess clustering on large scales. Our methods are tested against log-normal simulations with and without fNL and systematics, showing superior performance of the neural network treatment in reducing remaining systematics. Assuming the universality relation, we find fNL $= 47^{+14(+29)}_{-11(-22)}$ at 68\%(95\%) confidence. With a more aggressive treatment, including regression against the full set of imaging maps, our maximum likelihood value shifts slightly to fNL$\sim 50$ and the uncertainty on fNL increases due to the removal of large-scale clustering information. We apply a series of robustness tests (e.g., cuts on imaging, declination, or scales used) that show consistency in the obtained constraints. Despite extensive efforts to mitigate systematics, our measurements indicate fNL > 0 with a 99.9 percent confidence level. This outcome raises concerns as it could be attributed to unforeseen systematics, including calibration errors or uncertainties associated with low-\ell systematics in the extinction template. Alternatively, it could suggest a scale-dependent fNL model--causing significant non-Gaussianity around large-scale structure while leaving cosmic microwave background scales unaffected. Our results encourage further studies of fNL with DESI spectroscopic samples, where the inclusion of 3D clustering modes should help separate imaging systematics.Comment: 19 pages, 15 figures, 6 tables (Appendix excluded). Submitted to MNRA